I have serious Acid Reflux and had been prescribed Omeprazole (Prilosec OTC) for years -- all the while worrying about the side effects which can be very bad. Three months ago I decided on my own to try Turmeric Curcumin. Figured it's a spice used in food so what could it hurt. I take ONE Spring Valley Turmeric Curcumin 500 mg with 50 mg Ginger Powder in the morning at breakfast and ONE in the evening (it comes with the ginger in it. Read the label carefully because it also comes without the Ginger).